AMGN options flow: unusual options activity in Amgen Inc.
Updated 28 September 2026, 09:54 ET
Over the last week the tape recorded 93 unusual options prints in Amgen Inc. (AMGN), $6.3M of tracked premium, leaning bearish. Bullish premium was $2.0M against $3.1M bearish; $5.2M went into calls and $1.1M into puts, a put call ratio of 0.21. The largest print was $738K of AMGN 18 Dec 2026 $440 calls on 22 September 2026, swept below bid. The last session with prints, 28 September 2026, added 1 print and $40K of premium. AMGN closed at $414.61 on 25 September 2026, up 2.1%.
This week's unusual flow
Prints from 21 September 2026 to 28 September 2026, 6 sessions. Delayed tier: every print is shown twenty minutes after it executed, and the page is rebuilt after each session.
Net premium is bullish minus bearish premium. The put call ratio is put premium divided by call premium, weighted by money rather than by contract count. Sweeps is the share of prints executed across several exchanges at once. Read the guide: Reading the Pulse.
Largest prints of the week
| Date | Contract | Type | Size | Open int. | Premium | Execution | Sentiment | Tier |
|---|---|---|---|---|---|---|---|---|
| 22 Sep 2026 | AMGN 18 Dec 2026 $440 calls | Sweep | 843 | 393 | $738K | Below bid | Bearish | Whale |
| 23 Sep 2026 | AMGN 19 Jan 2029 $440 calls | Trade | 35 | 104 | $254K | At bid | Bearish | |
| 23 Sep 2026 | AMGN 19 Jan 2029 $440 calls | Trade | 35 | 104 | $253K | At bid | Bearish | |
| 23 Sep 2026 | AMGN 19 Jan 2029 $440 calls | Sweep | 30 | 104 | $217K | At ask | Bullish | Notable |
| 22 Sep 2026 | AMGN 16 Oct 2026 $395 calls | Trade | 117 | 646 | $161K | At bid | Bearish | |
| 23 Sep 2026 | AMGN 21 Jan 2028 $450 calls | Sweep | 35 | 212 | $160K | At ask | Neutral | |
| 23 Sep 2026 | AMGN 21 Jan 2028 $450 calls | Sweep | 35 | 212 | $159K | At ask | Neutral | |
| 21 Sep 2026 | AMGN 16 Oct 2026 $395 calls | Sweep | 149 | 274 | $146K | At ask | Bullish | Notable |
| 23 Sep 2026 | AMGN 21 Jan 2028 $450 calls | Sweep | 30 | 212 | $137K | At ask | Neutral | |
| 24 Sep 2026 | AMGN 15 Jan 2027 $410 calls | Trade | 50 | 614 | $130K | At bid | Bearish | |
| 24 Sep 2026 | AMGN 15 Jan 2027 $410 calls | Trade | 50 | 614 | $124K | At bid | Bearish | |
| 22 Sep 2026 | AMGN 16 Oct 2026 $410 puts | Sweep | 96 | 283 | $123K | Above ask | Bearish | Notable |
Size above open interest means the trade opened a position larger than everything that existed in the contract the night before. Above ask and below bid are the most aggressive executions. Read the guide: Size versus open interest.
Where the money is aimed
| Expiry | Prints | Premium | Calls share | Net premium |
|---|---|---|---|---|
| 18 Dec 2026 | 7 | $1.0M | 92% | -$566K |
| 16 Oct 2026 | 13 | $885K | 83% | +$123K |
| 21 Jan 2028 | 13 | $853K | 100% | +$139K |
| 19 Jan 2029 | 3 | $723K | 100% | -$290K |
| 2 Oct 2026 | 12 | $721K | 31% | -$309K |
| 17 Jun 2027 | 13 | $576K | 90% | -$62K |
The most premium, $1.0M, is aimed at the 18 Dec 2026 expiry; the nearest expiry with unusual prints is 2 Oct 2026.
A print in a contract expiring this week is a view about the next few days, often about a known event; a print months out is a different kind of statement. Read the guide: 0DTE options flow.
The last session, 28 September 2026
| Date | Contract | Type | Size | Open int. | Premium | Execution | Sentiment | Tier |
|---|---|---|---|---|---|---|---|---|
| 28 Sep 2026 | AMGN 16 Oct 2026 $400 calls | Trade | 20 | 984 | $40K | At ask | Bullish |
Every print in AMGN with its full detail, the live tape, one tap filters and saved screeners: open AMGN in Options Sentiment Screener.
Price
The live quote and the price chart sit beside the ticker's flow in the app: open AMGN in Options Sentiment Screener.
Analysts
The most recent analyst targets on file, from 22 firms, have a median of $402, 2.9% below the last close. The last 90 days brought 2 downgrades.
Calls bought at a strike above the average target are a bet that the analysts are too cautious; puts far below the price in a name they like are protection or a strong disagreement. Read the guide: Reading one ticker's flow.
About Amgen Inc.
- Exchange
- Nasdaq
- Sector
- Health Care
- Industry
- Pharmaceutical Products
- Headquarters
- Wilmington, California
- Website
- amgen.com
Amgen Inc. discovers, develops, manufactures, and delivers human therapeutics worldwide. It focuses on inflammation, oncology/hematology, bone health, cardiovascular disease, nephrology, and neuroscience areas. Its products include Enbrel to treat plaque psoriasis, rheumatoid arthritis, and psoriatic arthritis. Repatha reduces the risks of myocardial infarction, stroke, and coronary revascularization.
In the same sector
Flow pages for other Health Care names in the S&P 500:
LLY Eli Lilly & Co.JNJ Johnson & JohnsonABBV AbbVie Inc.MRK Merck & Co. Inc.UNH UnitedHealth Group Inc.TMO Thermo Fisher Scientific Inc.GILD Gilead Sciences, Inc.ABT Abbott Laboratories
Learn
- What unusual options activity means
- Reading one ticker's flow
- Sweeps, blocks and where a trade printed
- Size versus open interest
- Bullish or bearish, how a print's sentiment is inferred
- The conviction score and whale prints
The live tape for AMGN with every print's execution detail, one tap filters for calls, puts, sweeps and 0DTE, saved screeners and, for Realtime subscribers, push alerts and no delay. The same screen is in the iOS and Android apps.
Open AMGN in Options Sentiment Screener